Chlorite formulations and methods of preparation and use thereof
AssigneeNeuraltus Pharmaceuticals, Inc.
InventorsWilliam Boulanger, Arasteh Ari Azhir
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Abstract
Described herein are chlorite formulations having a pH between about 7 and about 8.5, wherein the chlorite formulations are substantially free of deleterious non-chlorite components. Described herein are chlorite formulations, including pharmaceutical formulations, which are formulated for systemic, parenteral, or intravenous administration. Described herein are methods of preparing and methods of using the chlorite formulations described herein.
Claims21
A method for treating a macrophage-associated neurodegenerative disease in a patient in need thereof comprising administering to said patient a composition comprising
- (i) a pharmaceutically acceptable salt of chlorite;
- (ii) a pH adjusting agent;
- and
- (iii) a pharmaceutically acceptable carrier;
- wherein said composition exhibits diminished cell toxicity relative to WF10.
Dependencies are inferred from the claim text.