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US 8,481,324 B2Granted
Apparatus and methods for diagnosing renal disorders
AssigneeTechnion Research & Development Foundation Limited
InventorsHossam Haick, Zaid Abassi, Farid Nakhoul
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Abstract
The present invention provides a system containing an array of chemically sensitive sensors based on coated single walled carbon nanotubes, for measuring volatile organic compounds indicative of renal failure. Methods of breath analysis for diagnosing chronic, acute and end-stage renal failure are disclosed.
Claims11
A method for diagnosing renal failure in a subject, the method comprising:
- (a) providing a system comprising an apparatus comprising an array of chemically sensitive sensors of single walled carbon nanotubes coated with an organic coating, wherein the organic coating comprises polymers or oligomers that are modified with at least one polar functional group;
- and a processing unit comprising a learning and pattern recognition analyzer wherein the learning and pattern recognition analyzer receives sensor signal output signals and compares them to stored data,
- (b) exposing the sensor array of the apparatus to a breath sample to detect volatile organic compounds in the breath sample, and
- (c) using a pattern recognition algorithm to determine the presence of the volatile organic compounds in the sample that are indicative of the renal failure in the subject, thereby providing a diagnosis of renal failure.
1 more element
Dependencies are inferred from the claim text.