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US 8,481,318 B2Granted
Nestin-expressing hair follicle stem cells
AssigneeAntiCancer, Inc.
InventorsLingna Li, Meng Yang
Life of this patent
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Abstract
Hair follicle stem cells are isolated in a method which relies on the identification of stem cells as being small, spindle, oval or round shaped nestin-expressing cells that are located in the permanent upper part of telogen hair follicles below the sebaceous glands and in the bulge area.
Claims3
A method to isolate hair follicle stem cells, which method comprises:
- (a) providing individual hair follicles from a mouse or human subject, wherein said hair follicles are in telogen or early anagen phase of the hair cycle;
- (b) obtaining small, spindle, oval or round shaped cells from the permanent upper part of the hair follicles right below the sebaceous glands;
- and
- (c) identifying the cells as nesting-expressing cells;
- wherein steps (b) and (c) of the method are performed in any sequential order or simultaneously.
2 more elements
Dependencies are inferred from the claim text.