Method of measuring electrical resistance value of corneal trans-epithelium

A method for measuring a corneal transepithelial electric resistance value comprising:

• (1) a step of preparing a voltage-electric resistance value measuring device, and a first electrode and a second electrode which are connected to the device;
• (2) a step of placing the first electrode on the cornea and the second electrode on the conjunctiva;
• and
• (3) a step of measuring the corneal transepithelial electric resistance value by flowing an electric current between the first electrode and the second electrode and through corneal epithelium to measure an electric resistance.

A device for measuring a corneal transepithelial electric resistance on a living eye, which comprises:

• (1) a first electrode suitable to be placed on a cornea,
• (2) a second electrode suitable to be placed on a conjunctiva, ˜d
• (3) an insulator that insulates the first electrode, and
• (4) a voltage-electric resistance value measuring device connected to the first electrode and the second electrode, wherein the device is capable of flowing an electric current through corneal epithelium,
• wherein the first electrode and the insulator are integrated, and
• wherein the insulator is made of silicone rubber, and the insulator has a contact surface to the cornea having the same curvature as that of the cornea.