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US 8,478,380 B2Granted
Magnetic resonance thermometry in the presence of water and fat
AssigneeWisconsin Alumni Research Foundation
InventorsBrian J. Soher, Scott B. Reeder
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Abstract
The in vivo measurement of tissue temperature is performed during a medical procedure using an MRI system. Fat and Water images are acquired at each temperature measurement time and corresponding phase images are produced. A temperature map is produced by subtracting the phase at each Fat image pixel from the corresponding pixel in the Water phase image to improve measurement accuracy in tissues with fat/water mixtures.
Claims8
A method for measuring the temperature of tissues containing a mixture of water and fat with a magnetic resonance imaging (MRI) system, the steps comprising:
- a) acquiring three image data sets by directing the MRI system to perform a pulse sequence that includes sampling three different echo signals during each repetition of the pulse sequence, each echo signal being formed at a different echo time;
- b) reconstructing a fat phase image from the acquired image data sets;
- c) reconstructing a water phase image from the acquired image data sets;
- and
- d) producing a temperature map which indicates the tissue temperature at each image voxel using the difference in phase between the water phase image and the fat phase image at the corresponding voxel.
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