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US 8,476,308 B2Granted
GPR120 receptor agonists and uses thereof
AssigneeMetabolex, Inc.
InventorsDong Fang Shi, Jiangao Song, Jingyuan Ma, Aaron Novack, Phuongly Pham, Imad Fayek Nashashibi, Christopher J. Rabbat, Xin Chen
Life of this patent
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Abstract
GPR120 agonists are provided. These compounds are useful for the treatment of metabolic diseases, including Type II diabetes and diseases associated with poor glycemic control.
Claims6
A compound selected from the group consisting of:
- 3-(4-((5-fluoro-1-(methoxycarbonyl)-2,2-dimethylindolin-7-yl)methoxy)-2,3-dimethylphenyl)propanoic acid;
- 3-(4-((5-fluoro-2,2-dimethylindolin-7-yl)methoxy)-2,3-dimethylphenyl)propanoic acid;
- and
- 3-(4-((5-fluoro-1,2,2-trimethylindolin-7-yl)methoxy)-2,3-dimethylphenyl)propanoic acid,
- or a pharmaceutically acceptable salt thereof.
2 more elements
Dependencies are inferred from the claim text.