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US 8,476,300 B2Granted
Selective estrogen receptor modulator for the treatment of osteoarthritis
AssigneeEli Lilly and Company
InventorsJeffrey Alan Dodge, Timothy Ivo Richardson, Christian Alexander Clarke, Scott Alan Jones, Ronald Jay Hinklin, Conrad Wilson Hummel, George Sal Lewis
Life of this patent
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Abstract
The present invention is directed to a compound of the formula (A): or a pharmaceutically acceptable salt thereof; and also to compounds of formula (I): or a pharmaceutically acceptable salt thereof.
Claims14
A compound of a formula
- or a pharmaceutically acceptable salt thereof;
- wherein
- R1 is selected from the group consisting of H, —C1-C4 alkyl, F, Cl, —CN, —C(O)R3, —(C1-C3 alkyl)OH, —OCH3, —S(O)2R4, —S(O)CH3, —CF3, and —S(C1-C3 alkyl);
- R2 is selected from the group consisting of H, F, and CH3;
- R3 is selected from the group consisting of OH, —OCH3, —NH(C0-C2 alkyl), CH3, —N(CH3)2;
- R4 is selected from the group consisting of —C1-C4 alkyl, —N(CH3)2, and —CF3;
- and
- R5 is selected from the group consisting of H and CH3.
5 more elements
Dependencies are inferred from the claim text.