1H-imidazo[4,5-c]quinolinone derivatives
AssigneeNovartis AG
InventorsPascal Furet, Frank Stephan Kalthoff, Robert Mah, Christian Ragot, Frédéric Stauffer
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AssigneeNovartis AG
InventorsPascal Furet, Frank Stephan Kalthoff, Robert Mah, Christian Ragot, Frédéric Stauffer
Estimating the term…
The invention relates to the use of 1H-imidazo[4,5-c]quinolinone derivatives and salts thereof in the treatment of protein and/or lipid kinase dependent diseases and for the manufacture of pharmaceutical preparations for the treatment of said diseases; 1H-imidazo[4,5-c]quinolinone derivatives for use in the treatment of protein and/or lipid kinase dependent diseases; a method of treatment against said diseases, comprising administering the 1H-imidazo[4,5-c]quinolinone derivatives to a warm-blooded animal, especially a human; pharmaceutical preparations comprising an 1H-imidazo[4,5-c]quinolinone derivative, especially for the treatment of a protein and/or lipid kinase dependent disease; novel 1H-imidazo[4,5-c]quinolinone derivatives; and a process for the preparation of the novel 1H-imidazo[4,5-c]quinolinone derivatives.
A pharmaceutical composition comprising a compound selected from 8-(2,4-dimethoxypyrimidin-5-yl)-1-(1-ethyl-3-methyl-1H-pyrazol-4-yl)-3-methyl-1H-imidazo[4,5-c]quinolin-2(3H)-one and 1-(1-ethyl-3-methyl-1H-pyrazol-4-yl)-8-(6-(methoxymethyl)-5-(methylamino)pyridin-3-yl)-3-methyl-1H-imidazo[4,5-c]quinolin-2(3H)-one, or a pharmaceutically acceptable salt thereof, and optionally a further therapeutic agent, together with a pharmaceutically acceptable carrier.
A compound of formula:
A compound of formula:
Dependencies are inferred from the claim text.