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US 8,476,271 B2Granted
Substituted-quinoxaline-type bridged-piperidine compounds as ORL-1 modulators
AssigneesPurdue Pharma L.P., Shionogi & Co., Ltd.
InventorsNaoki Tsuno, Jiangchao Yao
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Abstract
Compounds of Formula (I): where R1, R2, R5, a, and b are disclosed herein, and pharmaceutically acceptable derivatives thereof (a “Substituted-Quinoxaline-Type Bridged-Piperidine Compound”), compositions comprising an effective amount of a Substituted-Quinoxaline-Type Bridged-Piperidine Compound, and methods to treat or prevent a condition, such as pain, comprising administering to an animal in need thereof an effective amount of a Substituted-Quinoxaline-Type Bridged-Piperidine Compound.
Claims51
A compound having the formula:
- or a pharmaceutically acceptable salt thereof.
A compound having the formula:
- or a pharmaceutically acceptable salt thereof.
A compound having the formula:
Dependencies are inferred from the claim text.