Imidazo-, pyrazolopyrazines and imidazotriazines and their use

A compound of the formula,

• characterized in that
• either
• U represents N,
• V represents CR12,
• W represents CH,
• A represents CR15,
• or
• U represents CH,
• V represents CR12,
• W represents N,
• A represents CR15,
• or
• U represents CR16,
• V represents N,
• W represents CR17,
• A represents N,
• where
• R12 represents hydrogen, hydroxycarbonyl, aminocarbonyl, methyl, ethyl, C1-C4-alkylcarbonyl, C1-C4-alkoxycarbonyl, C1-C4-alkylaminocarbonyl, C1-C4-alkylcarbonylamino, pyrrolidinylcarbonyl, piperidinylcarbonyl, piperazinylcarbonyl, morpholinylcarbonyl or —CH2R13′
• where pyrrolidinylcarbonyl, piperidinylcarbonyl, piperazinylcarbonyl and morpholinylcarbonyl may be substituted by 1 to 2 substituents, where the substituents independently of one another are selected from the group consisting of oxo, methyl and ethyl,
• and
• where alkylcarbonyl, C2-C4-alkoxycarbonyl and C2-C4-alkylaminocarbonyl may be substituted by a substituent, where the substituent is selected from the group consisting of hydroxyl, amino, C1-C4-alkylamino, pyrrolidinyl, piperidinyl, piperazinyl and morpholinyl,
• where pyrrolidinyl, piperidinyl, piperazinyl and morpholinyl may be substituted by 1 to 2 substituents, where the substituents independently of one another are selected from the group consisting of oxo, methyl and ethyl,
• and
• where
• R13 represents hydroxyl, amino, hydroxycarbonyl, aminocarbonyl, C1-C4-alkoxy, C1-C4-alkylamino, pyrrolidinyl, piperidinyl, piperazinyl or morpholinyl,
• where pyrrolidinyl, piperidinyl, piperazinyl and morpholinyl may be substituted by 1 to 2 substituents, where the substituents independently of one another are selected from the group consisting of oxo, methyl and ethyl,
• R15 represents hydrogen,
• R16 represents hydrogen or methyl,
• R17 represents hydrogen or methyl,
• R1 represents a group of the formula
• where
• * is the point of attachment to the heterocycle,
• n represents the number 0,
• X represents NR10,
• where
• R10 represents hydrogen,
• Y represents NR11,
• where
• R11 represents hydrogen or methyl,
• R3 represents 2-pyridyl, pyrimid-2-yl, 2-aminopyrimid-4-yl, 1,3-thiazol-2-yl or 1,3-thiazol-4-yl, where 2-pyridyl, pyrimid-2-yl, 1,3-thiazol-2-yl and 1,3-thiazol-4-yl are substituted by 1 or 2 substituents, where the substituents independently of one another are selected from the group consisting of fluorine, chlorine, cyano, nitro, amino and trifluoromethyl,
• and
• where 2-aminopyrimid-4-yl may be substituted by a substituent, where the substituent is selected from the group consisting of fluorine, chlorine, cyano, nitro, amino and trifluoromethyl,
• R4 represents hydrogen,
• R5 represents hydrogen or methyl,
• R6 represents hydrogen,
• R7 represents hydrogen or methyl,
• R8 represents hydrogen,
• R9 represents hydrogen or methyl,
• R2 represents phenyl, thienyl, pyrazolyl or pyridyl,
• where phenyl, thienyl, pyrazolyl and pyridyl may be substituted by 1 to 2 substituents, where the substituents independently of one another are selected from the group consisting of halogen, trifluoromethyl, trifluoromethoxy, aminocarbonyl, C1-C4-alkyl, C1-C4-alkoxy, C1-C4-alkoxycarbonyl, C1-C4-alkylaminocarbonyl, pyrrolidinyl, piperidinyl, morpholinyl and morpholinylcarbonyl,
• or one of its salts.