US 8,476,073 B2Granted

Automatic analyzing apparatus and quality control method for analysis supporting liquid in the same

AssigneeBeckman Coulter, Inc.

InventorAkihisa Kuroda

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Abstract

An automatic analyzing apparatus can properly determine a quality of an analysis supporting liquid, after being supplied to the automatic analyzing apparatus, which supports an analysis performed in the automatic analyzing apparatus and can properly maintain an accuracy of the analysis. The analysis supporting liquid which supports an analysis of a specimen is dispensed into a reaction vessel by using a specimen dispensing unit which dispenses the specimen, a reagent dispensing unit which dispenses a reagent, a cleaning unit which cleans the reaction vessel, or a diluted solution dispensing unit which dispenses a diluted solution. An optical measurement is performed with respect to a liquid including the dispensed analysis supporting liquid in the reaction vessel. Analysis data of the analysis supporting liquid is generated by using the measured result. The quality of the analysis supporting liquid is determined by comparing the generated analysis data with reference data.

Claims7

Dependent claims

A quality control method for an analysis supporting liquid in an automatic analyzing apparatus which includes, to perform an analysis on a specimen, a specimen dispensing unit which dispenses the specimen by using, as a pressure transmitting medium, an analysis supporting liquid including purified water and serving to support the analysis on the specimen, a reagent dispensing unit which dispenses a reagent by using the analysis supporting liquid as the pressure transmitting medium, a cleaning unit which cleans, by using the analysis supporting liquid as a cleaning liquid, a reaction vessel in which the specimen and the reagent are mixed and made to react to each other, and a diluted solution dispensing unit which dispenses a diluted solution including the analysis supporting liquid, and which controls a quality of the analysis supporting liquid, the quality control method for the analysis supporting liquid comprising:

dispensing the analysis supporting liquid into the reaction vessel by one of the specimen dispensing unit, the reagent dispensing unit, the cleaning unit, and the diluted solution dispensing unit;
performing an optical measurement with respect to a liquid, including the analysis supporting liquid dispensed in the dispensing, in the reaction vessel, wherein the optical measurement is performed prior to any reaction using said liquid including said analysis supporting liquid;
generating analysis data of the analysis supporting liquid by using a result measured from the optical measurement;
and
determining whether the quality of the analysis supporting liquid is outside a predetermined range by comparing the analysis data generated in the data generating with reference data,
wherein when it is determined that the quality is outside the predetermined range, adjusting a setting of the automatic analyzing apparatus for analyzing the specimen, said adjusting based on a predetermined rule reflective of quality control requirements for the analysis supporting liquid.

3 more elements

An automatic analyzing apparatus, comprising:

a specimen dispensing unit which dispenses a specimen by using, as a pressure transmitting medium, an analysis supporting liquid including purified water and serving to support an analysis on the specimen;
a reagent dispensing unit which dispenses a reagent by using the analysis supporting liquid as the pressure transmitting medium;
a cleaning unit which cleans, by using the analysis supporting liquid as a cleaning liquid, a reaction vessel in which the specimen and the reagent are mixed and made to react to each other;
a diluted solution dispensing unit which dispenses a diluted solution including the analysis supporting liquid;
a photometric unit which performs an optical measurement with respect to a liquid including the analysis supporting liquid dispensed into the reaction vessel by one of the specimen dispensing unit, the reagent dispensing unit, the cleaning unit, and the diluted solution dispensing unit, wherein the optical measurement is performed prior to any reaction using said liquid including said analysis supporting liquid;
a data generating unit which uses a result measured by the photometric unit to generate analysis data of the analysis supporting liquid;
a quality determining unit which compares the analysis data generated by the data generating unit with reference data to determine whether a quality of the analysis supporting liquid is outside a predetermined range, and
a control unit, which when it is determined by the quality determining unit that the quality is outside the predetermined range, adjusts a setting of the automatic analyzing apparatus for analyzing the specimen, said adjusting based on a predetermined rule reflective of quality control requirements for the analysis supporting liquid.

5 more elements

Dependencies are inferred from the claim text.

Facts

Application: 12/248,444Filed 9 Oct 2008 · continuation
Priority: JP 2006-10971912 Apr 2006
Published: US 2009/0087914 A12 Apr 2009
Granted: 2 Jul 2013
Term ends: Not estimatedThe source records don’t support an estimate.

Classification5 codes

G01N 35/00663
Quality control: of consumables
Y10T 436/11
Chemistry: analytical and immunological testing: automated chemical analysis
Y10T 436/115831
Automated chemical analysis: condition or time responsive
G01N
Investigating or analysing materials by determining their chemical or physical properties