Topical patch for pain relief using cooling agent
AssigneeTeikoku Pharma USA, Inc.
InventorJutaro Shudo
Life of this patent
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Abstract
Topical patch preparations that contain an odorless physiological cooling agent, and methods for using the same are provided. The subject topical patch preparations are made up of an adhesive gel composition that is present on a support, where the adhesive gel composition includes the odorless physiological cooling agent, a water-soluble polymer gel, water and a water holding agent. In using the subject topical patch preparations, the topical patch preparations are applied to a skin surface of a subject and maintained at the site of application for a period of time sufficient for an effective amount of the an odorless physiological cooling agent to be administered to the subject. The subject invention finds use in a variety of applications.
Claims11
A topical patch preparation comprising:
- (a) an adhesive gel composition having a pH ranging from about 4.0 to 7.0 and comprising:
- (i) a drug consisting of N,2,3-trimethyl-2-isopropylbutamide in a pain-relieving effective amount ranging from about 0.1 to 15.0% (w/w);
- (ii) a water-soluble polymer gel;
- (iii) water in an amount ranging from about 10 to 80% (w/w);
- and
- (iv) a water retaining agent;
- and
- (b) a support.
A topical patch preparation comprising:
- (a) an adhesive gel composition having a pH ranging from about 4.0 to 6.0 and comprising:
- (i) a drug consisting of N,2,3-trimethyl-2-isopropylbutamide in a pain-relieving effective amount ranging from about 0.5 to 10.0% (w/w);
- (ii) a water-soluble polymer gel;
- (iii) water in an amount ranging from about 30 to 60% (w/w);
- (iv) a water retaining agent;
- (b) a support.
A method of delivering N,2,3-trimethyl-2-isopropylbutamide to a subject, said method comprising:
- (a) applying a topical patch preparation comprising:
- (i) an adhesive gel composition comprising a drug consisting of a pain-relieving effective amount of N,2,3-trimethyl-2-isopropylbutamide;
- and
- (ii) a support;
- to a skin surface of said subject;
- and
- (b) maintaining said topical patch preparation on said skin surface for a period of time sufficient for said N,2,3-trimethyl-2-isopropylbutamide to be delivered to said subject.
A kit comprising:
- (a) a topical patch preparation comprising:
- (i) an adhesive gel composition comprising a drug consisting of a pain-relieving effective amount of N,2,3-trimethyl-2-isopropylbutamide;
- and
- (ii) a support;
- and
- (b) instructions for using said preparation.
Dependencies are inferred from the claim text.