Transdermal preparation
AssigneeHisamitsu Pharmaceutical Co., Inc.
InventorsSatoshi Amano, Tomohiro Shinoda, Natsumi Kase
Life of this patent
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Abstract
Provided is a transdermal preparation, which is capable of long-term (1-day to 7-day) release of a basic drug from a preparation, continuously and at a consistent concentration; shows little reduction over time in the drug content, even if multiple drugs are contained in the preparation; and is produced by a simple process. The transdermal preparation comprises a substrate, and an adhesive layer containing a basic drug and a water-soluble polymer.
Claims14
A transdermal preparation having a backing and an adhesive layer for delivering a selected amount of bisoprolol through the skin continuously for a period of 1 to 7 day(s), wherein the adhesive layer comprises multiple layers, said multiple layers comprising a drug reservoir layer and a skin adhesion layer;
- wherein said drug reservoir layer comprises bisoprolol at 30-50 mass % based on the total amount of the drug reservoir layer and a water-soluble polymer;
- and wherein the weight ratio of bisoprolol to the water-soluble polymer in the drug reservoir layer is from 35:65 to 55:45.
Dependencies are inferred from the claim text.