Peptide sequences and compositions
AssigneePep T cell Limited
InventorsGregory Alan Stoloff, Wilson Romero Caparros-Wanderley
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Abstract
Provided is a polypeptide having no more than 100 amino acids, which polypeptide has one or more sequences having at least 60% homology with any of SEQ ID 1-6, or has two or more epitopes having 7 amino acids or more, each epitope having at least 60% homology with a sub-sequence of any of SEQ ID 1-6 that has the same length as the epitope: SEQ ID 1 DLEALMEWLKTRPILSPLTKGILGFVFTLTVP SEQ ID 2 LLYCLMVMYLNPGNYSMQVKLGTLCALCEKQASHS SEQ ID 3 DLIFLARSALILRGSVAHKSC SEQ ID 4 PGIADIEDLTLLARSMVVVRP SEQ ID 5 LLIDGTASLSPGMMMGMFNMLSTVLGVSILNLGQ SEQ ID 6 IIGILHLILWILDRLFFKCIYRLF wherein, the polypeptide is immunogenic in a vertebrate expressing a major histocompatibility complex (MHC) allele, and wherein the polypeptide is not a complete influenza virus protein.
Claims31
An isolated polypeptide consisting of SEQ ID NO:
- 1.
A composition comprising an isolated immunogenic multi-epitope polypeptide comprising SEQ ID NO:1 and SEQ ID NO:2 , wherein each sequence includes two or more epitopes each having 7 or more amino acids.
Dependencies are inferred from the claim text.