Phosphorylated derivatives of a U1-70K peptide and their use in the treatment of autoimmune pathologies
AssigneeCentre National De La Recherche Scientifique
InventorsSylviane Muller, Fanny Sylvie Michele Monneaux, Jean-Paul Briand, Gilles Guichard, Jean-Gerard Guillet
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Abstract
Derivatives of the peptide corresponding to the sequence RIHMVYSKRSGKPRGYAFIEY (SEQ ID NO: 1), pharmaceutical compositions, and methods of use thereof are provided.
Claims8
A method of treating systemic lupus erythematosus (SLE) in a patient, comprising the step of administering to the patient the peptide having the amino acid sequence set forth in SEQ ID NO:
- 1, wherein the serine residue in position 10 is phosphorylated, or a salt thereof.
A method of treating systemic lupus erythematosus (SLE) in a patient, comprising the step of administering to the patient a pharmaceutical composition comprising the peptide having the amino acid sequence set forth in SEQ ID NO:
- 1, wherein the serine residue in position 10 is phosphorylated, or a salt thereof, and a pharmaceutically acceptable vehicle.
Dependencies are inferred from the claim text.