Method of treating pain using an antagonist of GM-CSF
AssigneeThe University of Melbourne
InventorsJohn Allan Hamilton, Andrew David Cook
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Abstract
The present invention relates generally to a method for the treatment and prophylaxis of pain. In accordance with the present invention, it is proposed that antagonists of GM-CSF are effective in the treatment of pain. Antagonists of GM-CSF include, but are not limited to, antibodies which are specific for GM-CSF or the GM-CSF receptor. The present invention further provides transgenic animals, such as a GM-CSF knock-out mouse, useful for testing antagonists in certain disease models.
Claims7
A method for the treatment of pain in a subject, comprising administering to the subject an antagonist of GM-CSF, wherein said antagonist is an antibody specific for GM-CSF or the GM-CSF receptor, wherein said pain is selected from bone cancer pain, osteoarthritic pain and post-surgical pain.
Dependencies are inferred from the claim text.