Ion binding polymers and uses thereof
AssigneeRelypsa, Inc.
InventorsDominique Charmot, Han-Ting Chang, Gerrit Klaerner, Jerry M. Buysse, Mingjun Liu
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Abstract
The present invention provides methods and compositions for the treatment of ion imbalances. In particular, the invention provides compositions comprising potassium binding polymers and pharmaceutical compositions thereof. Methods of use of the polymeric and pharmaceutical compositions for therapeutic and/or prophylactic benefits are disclosed herein. Examples of these methods include the treatment of hyperkalemia, such as hyperkalemia caused by renal failure and/or the use of hyperkalemia causing drugs.
Claims18
A method of treating hyperkalemia in a patient in need thereof, the method comprising administering a pharmaceutical composition to the patient, wherein the administration is oral, intestinal, or rectal, the patient being treated with a drug that may cause hyperkalemia, wherein the pharmaceutical composition comprises a crosslinked polymer having moieties comprising one or more of the following structures:
- or an acid or salt thereof.
A method of treating a patient, the method comprising administering to the patient a drug that may cause hyperkalemia and a pharmaceutical composition, wherein the pharmaceutical composition comprises a crosslinked polymer having moieties comprising one or more of the following structures:
- or an acid or salt thereof.
Dependencies are inferred from the claim text.