Renal denervation and stimulation employing wireless vascular energy transfer arrangement
AssigneeBoston Scientific Scimed, Inc.
InventorsRoger Hastings, Anthony Vrba, Clara Davis
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Abstract
Devices, systems, and methods provide for intravascular or extravascular delivery of renal denervation therapy and/or renal control stimulation therapy. Wireless vascular thermal transfer apparatuses and methods provide for one or both of production of current densities sufficient to ablate renal nerves and terminate renal sympathetic nerve activity, and production of current densities sufficient to induce endothelium dependent vasodilation of the renal artery bed. A common apparatus may be used for both renal ablation and control of renal function locally after renal denervation.
Claims13
An apparatus for delivering a therapy to a renal artery of a patient, comprising:
- a support structure dimensioned for deployment at the renal artery, the support structure configured for chronic fixation at the renal artery;
- a thermal transfer arrangement supported by the support structure and comprising one or more thermoelectric elements configured to thermally couple to the renal artery and capable of operating in at least one of a hyperthermic configuration and a hypothermic configuration;
- power circuitry supported by the support structure and coupled to the thermal transfer arrangement, the power circuit comprising a receiver configured to receive energy from a power source external of the renal artery, the power source supplying energy to the receiver other than by way of a percutaneous lead;
- and
- a control circuit supported by the support structure and coupled to the power circuitry, wherein the control circuit, if in the hyperthermic configuration, is configured to coordinate delivery of hyperthermic ablation therapy to ablate innervated renal nerve tissue at or proximate the renal artery and, if in the hyporthermic configuration, is configured to coordinate delivery of hypothermic ablation therapy to freeze innervated renal nerve tissue at or proximate the renal artery.
A method for delivering a therapy to a renal artery of a patient, comprising:
- receiving energy by a receiver supported by a support structure adapted for chronic fixation within the renal artery from a power source external of the renal artery;
- communicating the energy received by the receiver to a power circuit supported by the support structure;
- supplying power from the power circuit to a thermal transfer arrangement supported by the support structure and comprising one or more thermoelectric elements configured to thermally couple to the renal artery;
- and
- operating the receiver and the power circuit in at least one of:
- a hyperthermic configuration for delivering a hyperthermic therapy to ablate innervated renal nerve tissue at or proximate the renal artery;
- and
- a hypothermic configuration for delivering a hypothermic therapy to freeze innervated renal nerve tissue at or proximate the renal artery;
- wherein the power source supplies energy to the receiver other than by way of a percutaneous electrical lead.
Dependencies are inferred from the claim text.