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US 8,470,815 B2Granted
Nitrofuran compounds for the treatment of cancer and angiogenesis
AssigneesBrown University, Women & Infants Hospital of Rhode Island
InventorsGiselle L. Saulnier Sholler, Narasimha Swamy, Satyan Kalkunte, Rakesh K. Singh, Laurent Brard, Kyu Kwang Kim
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Abstract
The invention is directed to the synthesis and use of nitrofuran compounds, especially Nifurtimox, as medicaments to treat cancer, especially neuroblastoma, and to inhibit angiogenesis. The invention also provides compositions, unit dosage forms, and kits comprising the compounds.
Claims12
A method for treating a cancer or inhibiting angiogenesis in a mammal, comprising the step of:
- administering to a mammal having the cancer a therapeutically effective amount of Nifurtimox.
Dependencies are inferred from the claim text.