Method and medicament for inhibiting the infection of influenza virus
AssigneeInstitute of Microbiology, Chinese Academy of Sciences
InventorsGeorge Fu Gao, June Liu, Po Tien
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Abstract
The invention relates to a process for inhibiting the infection of influenza viruses and a polypeptide or protein medicine used therein. More particularly, the invention involves a process for inhibiting the highly pathogenic avian influenza virus (such as H5N1 subtype) infection and human influenza virus (such as H1N1 subtype and H3N2 subtype) infection, as well as the polypeptide or protein involved therein, and a polynucleotide encoding the polypeptide or protein and a vector or host cell expressing said polypeptide or protein.
Claims12
An isolated polypeptide, wherein the amino acid sequence of said polypeptide consists of SEQ ID NO:
- 1, 2, 3, 4, 5, 21, 22 or 23.
An isolated polypeptide comprising:
- (a) a first polypeptide consisting of SEQ ID NO:
- 1, 2 or 3;
- (b) a second polypeptide consisting of SEQ ID NO:
- 4, 5, 21, 22 or 23;
- and
- (c) an exogenous linking peptide that connects said first and second polypeptides, said linking peptide comprising at least one of glycine, serine, proline, and alanine.
Dependencies are inferred from the claim text.