Methods and compositions for producing squalene using yeast
AssigneeNucelis LLC
InventorsKeith A. Walker, Mark E. Knuth, Noel M. Fong, Peter R. Beetham
Life of this patent
Estimating the term…
Abstract
Provided herein compositions and methods for producing isoprenoids, including squalene. In certain aspects and embodiments provided are genetically converted yeast and uses therefore. In some aspects and embodiments, the genetically converted yeast produce isoprenoids, preferably squalene. Also are provided methods of producing squalene using a genetically converted yeast or a non-genetically converted yeast. The invention also provides squalene produced by genetically converted yeast or non-genetically converted yeast.
Claims10
A method of producing squalene by a genetically converted or non-genetically converted yeast, said method comprising
- cultivating said yeast with an antifungal agent;
- wherein the yeast is a Yarrowia lipolytica strain selected from the group consisting of ATCC 20688, ATCC 90811, ATCC 90904, ATCC 90812, ATCC MYA-2613, and Yeastern polg, and wherein the antifungal agent is an allylamine antifungal agent.
Dependencies are inferred from the claim text.