# US 8,464,713 B2 · Automated inspiratory muscle training for patients receiving mechanical ventilation

> Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt

- Number: US 8,464,713 B2
- Document ID: US8464713B2
- Status: Granted
- Kind: B2
- Application number: 13/556,546
- Filed: 2012-07-24
- Published: 2012-11-15
- Granted: 2013-06-18
- Earliest claimed: 2008-03-10
- Assignees: University of Florida Research Foundation, Inc.
- Applicants: Anatole D. Martin; Michael J. Banner; Andrea Gabrielli; Neil Russell Euliano, II
- Inventors: Anatole D. Martin; Michael J. Banner; Andrea Gabrielli; Neil Russell Euliano, II
- Web page: https://patentgrep.com/patent/US8464713B2

## CPC

- A61M 16/0057: {Pumps therefor}
- A61B 5/087: Measuring breath flow
- A61B 5/412: {Detecting or monitoring sepsis}
- A61M 16/026: {specially adapted for predicting, e.g. for determining an information representative of a flow limitation during a ventilation cycle by using a root square technique or a regression analysis}
- A61M 16/20: Valves specially adapted to medical respiratory devices
- A61M 16/204: {used for inhalation control}
- A61M 16/205: {used for exhalation control}
- A61M 2016/0027: {pressure meter}
- A61M 2016/0039: {in the inspiratory circuit}
- A61M 2016/0042: {in the expiratory circuit}
- A61M 2205/502: User interfaces, e.g. screens or keyboards
- A61M 2230/40: Respiratory characteristics
- A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)}
- A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D)

## Abstract

A system and method for automated inspiratory muscle strength exercise includes software for setting a mechanical ventilator for a pressure regulated breath with an initial pressure target that is at the highest pressure setting a patient can tolerate and increasing the pressure target as tolerated.

## Claims

### Claim 1

One or more computer-readable media having computer-useable instructions embodied thereon for performing a method of inspiratory muscle strength training, the method comprising:
providing a sensing assembly and gas delivery device having an inhalation assembly that provides inspiratory air flow to a patient;
imposing delivery of inspiratory air flow using an inspiratory training stimulus; and
controlling the inhalation assembly to deliver inspiratory air flow using the inspiratory training stimulus during an entire inhalation act for every breath by the patient.

### Claim 2 (depends on 1)

The media of claim 1, wherein the gas delivery device is a mechanical ventilator.

### Claim 3 (depends on 1)

The media of claim 1, wherein the inspiratory training stimulus is a pressure between 1 to 80 cm of H2O.

### Claim 4 (depends on 3)

The media of claim 3, wherein the inspiratory training pressure is between 2-20 cm of H2O.

### Claim 5

One or more computer-readable media having computer-useable instructions embodied thereon for performing a method of inspiratory muscle strength training, the method comprising:
receiving respiratory parameters of a patient from a sensing assembly;
calculating an inspiratory training stimulus variable from the respiratory parameters; and
providing said inspiratory training stimulus variable to a gas delivery device, wherein said gas delivery device delivers inspiratory air flow to the patient and comprises settings for adjusting the inspiratory airflow; and
adjusting the gas delivery settings to administer air flow to the patient to impose negative pressure on the patient during inhalation at the inspiratory training stimulus variable.

### Claim 6 (depends on 5)

The media of claim 5, wherein the gas delivery device is a mechanical ventilator.

### Claim 7 (depends on 5)

The media of claim 5, wherein the inspiratory training stimulus is a pressure between 1 to 80 cm of H2O.

### Claim 8 (depends on 7)

The media of claim 7, wherein the inspiratory training pressure is between 2-20 cm of H2O.

### Claim 9 (depends on 5)

The media of claim 5, wherein the inspiratory training stimulus is a target power of breathing.

### Claim 10 (depends on 5)

The media of claim 5, wherein the method further comprises:
receiving a second set of respiratory parameters of the patient comprising a response of the patient to the inspiratory training stimulus;
calculating a second inspiratory training stimulus variable from the second set of respiratory parameters;
providing said second inspiratory training stimulus variable to the gas delivery device;
adjusting the gas delivery settings to administer air flow to the patient to impose negative pressure on the patient during inhalation at the second inspiratory training stimulus variable; and
repeating the steps herein as necessary.