# US 8,464,553 B2 · Production of a pharmaceutical container from the melt > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 8,464,553 B2 - Document ID: US8464553B2 - Status: Granted - Kind: B2 - Application number: 12/700,762 - Filed: 2010-02-05 - Published: 2010-08-12 - Granted: 2013-06-18 - Earliest claimed: 2009-02-06 - Assignees: Schott AG - Applicants: Andreas Langsdorf; Juergen Thuerk; Aurel Kunz; Ulrich Lange; Joachim Kuester; Bernd Loeffelbein; Marcus Meinefeld; Uwe Rothhaar; Axel Ohlinger - Inventors: Andreas Langsdorf; Juergen Thuerk; Aurel Kunz; Ulrich Lange; Joachim Kuester; Bernd Loeffelbein; Marcus Meinefeld; Uwe Rothhaar; Axel Ohlinger - Web page: https://patentgrep.com/patent/US8464553B2 ## CPC - A61J 1/05: for collecting, storing or administering blood, plasma or medical fluids {(multiple bags systems for separating or storing blood components A61M1/0209); Infusion or perfusion containers} - A61M 5/3129: {Syringe barrels (A61M5/3205, A61M5/50 take precedence)} - C03B 9/193: in "press-and-blow" machines - C03B 9/1932: {Details of such machines, e.g. plungers or plunger mechanisms for the press-and-blow machine, cooling of plungers (C03B9/195 takes precedence)} - A61J 1/00: Containers specially adapted for medical or pharmaceutical purposes (capsules or the like for oral use A61J3/07; specially adapted for surgical or diagnostic appliances or instruments A61B50/30; containers for radioactive substances G21F5/00) - Y10T 428/131: Glass, ceramic, or sintered, fused, fired, or calcined metal oxide or metal carbide containing [e.g., porcelain, brick, cement, etc.] - A61J: CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE - A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)} - C03B: MANUFACTURE, SHAPING, OR SUPPLEMENTARY PROCESSES - Y10T: TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION ## Abstract The invention proposes a process for the production of a container for pharmaceutical and medical applications made from glass, preferably from a borosilicate glass, wherein the container is produced by a press-blow process where the container is initially preformed in a pressing step, by making a ram press a dispensed glass drop into a mold that is open at its bottom, and where the parison so produced is given its final form by a subsequent blowing step. ## Claims ### Claim 1 The process of producing a container from glass, the container having a shape of a hollow body open on both ends, the process comprising the steps of: providing a mold having an open top and an open bottom; providing a ram; melting a glass; dispensing a molten glass drop into said mold; striking said ram down into said mold for pressing said glass drop, thereby preforming a parison; heating said parison in a medium portion thereof to a temperature at which viscosity of said glass is less than 104.7 dPas; and blowing said parison while rotating said parison for near-net shaping a container form of said parison; wherein said striking and pressing step comprises in a first pressing step preforming the parison using a first ram without a cone channel; removing said first ram; and in a second pressing step pressing a second ram into said parison for shaping a cone channel in said parison. ### Claim 2 (depends on 1) The process of claim 1, wherein said container is produced with a cylindrical medium portion with a flange at its one end and a cone on its other end; and wherein said second ram is moved toward said flange from a side opposite thereof. ### Claim 3 (depends on 2) The process of claim 2, wherein the container is produced with a full-length cone channel in its cone. ### Claim 4 (depends on 2) The process of claim 2, wherein the parison has a wall thickness that tapers from the cone toward the flange in the cylindrical portion of the container. ### Claim 5 (depends on 1) The process of claim 1, wherein the parison is given substantially the form of a hollow truncated cone in the pressing step. ### Claim 6 (depends on 1) The process of claim 1, wherein the parison is cooled on at least one of its two ends after the down stroke of the first ram to a temperature at which viscosity of the glass is less than 1010 dPas. ### Claim 7 (depends on 1) The process of claim 1, wherein the glass drop is dispensed directly into said mold and is then pressed into said mold by said first ram. ### Claim 8 (depends on 1) The process of claim 1, wherein the cone is cut off at an outer end thereof in order to open up the cone channel. ### Claim 9 (depends on 1) The process of claim 1, wherein the parison is cooled on at least one of its two ends after the down stroke of the second ram to a temperature at which viscosity of the glass is less than 1010 dPas. ### Claim 10 (depends on 1) The process of claim 1, wherein a vacuum is applied during said first pressing step. ### Claim 11 (depends on 1) The process of claim 1, wherein a vacuum is applied during said second pressing step. ### Claim 12 A process of producing a container from glass, the container having a shape of a hollow body open on both ends, the process comprising the steps of: providing a mold having an open top and an open bottom; providing a ram; melting a glass; dispensing a molten glass drop into said mold; striking said ram down into said mold for pressing said glass drop, thereby preforming a parison; heating said parison in a medium portion thereof to a temperature at which viscosity of said glass is less than 104.7 dPas; and blowing said parison while rotating said parison for near-net shaping a container form of said parison; wherein the container is produced with a cylindrical medium portion with a flange at its one end and a cone on its other end; and a parison is formed in a first pressing step, using a ram that is conical over its full length; said ram is replaced in a subsequent step by a mandrel having the shape of a cone channel; said parison is driven to rotate; and molding rolls are pressed from the outside against said parison in a region of the cone for shaping said parison. ### Claim 13 (depends on 12) The process of claim 12, wherein said parison is reheated in a region of the cone before said molding rolls are applied against said parison. ### Claim 14 (depends on 12) The process of claim 12, wherein a vacuum is applied during said pressing step. ### Claim 15 A process of producing a container from glass, the container having a shape of a hollow body open on both ends, the process comprising the steps of: providing a mold having an open top and an open bottom; providing a ram; melting a glass; dispensing a molten glass drop into said mold; striking said ram down into said mold for pressing said glass drop, thereby preforming a parison; heating said parison in a medium portion thereof to a temperature at which viscosity of said glass is less than 104.7 dPas; and blowing said parison while rotating said parison for near-net shaping a container form of said parison; wherein the container is produced with a cylindrical medium portion with a flange at its one end and a cone on its other end; and wherein said cone channel is produced by a stroke of a mandrel guided in said ram, after the glass volume supplied has been shaped in the pressing step.