Glycolipid adjuvant compositions

A composition comprising:

• a) a glycolipid of Formula I;
• wherein Formula I is
• wherein
• R1 is hydrogen, or a saturated alkyl radical having up to 20 carbon atoms;
• X is —CH2—, —O— or —NH—;
• R2 is hydrogen, or a saturated or unsaturated alkyl radical having up to 20 carbon atoms;
• R3, R4, and R5 are independently hydrogen, —SO42−, —PO42−, or —COC1-10alkyl;
• R6 is L-alanyl, L-alpha-aminobutyl, L-arginyl, L-asparginyl, L-aspartyl, L-cysteinyl, L-glutamyl, L-glycyl, L-histidyl, L-hydroxyprolyl, L-isoleucyl, L-leucyl, L-lysyl, L -methionyl, L-ornithinyl, L-phenylalanyl;
• L-prolyl, L-seryl, L-threonyl, L-tyrosyl, L -tryptophanyl, or L-valyl, or their D-isomers;
• in a salt form, where the salt form is derived from a weak acid,
• b) an alcohol, wherein the alcohol is HO—C1-3 alkyl;
• c) a weak acid, wherein the weak acid is, 1) in molar excess with reference to the glycolipid content, and 2) any acid having a pKa (the −log of the Ka) value of between 1.0 and 9.5;
• d) a non-ionic surfactant, where the non-ionic surfactant is an agent that reduces the surface tension of the material it is dissolved in and has a component that is hydrophobic and another component that is hydrophilic;
• further wherein the composition is stable for up to one year, shows little or no flocculation for up to one year, has a pH from about 6 to about 8, and has an optical density of about 1.0 or less.