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US 8,449,171 B2Granted
Method for microfluidic mixing and mixing device
AssigneeCommonwealth Scientific and Industrial Research Organisation
InventorsPaul Mun Foo Tho, Richard Manasseh, Yonggang Zhu, Guy Metcalfe
Life of this patent
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Abstract
A method of mixing (10), including: providing a fluid (10) in a well (6) so as to establish an acoustic field gradient; and applying an acoustic signal to cause mixing within a fluid (3).
Claims21
A method of mixing within a liquid, including:
- providing a liquid-gas interface so as to establish an acoustic field gradient;
- applying a first acoustic signal to the liquid to cause the interface to oscillate with a first mode of oscillation, thereby creating a first streaming pattern having first streamlines within the liquid;
- and
- after applying the first acoustic signal, applying a second acoustic signal that is discretely separate from the first acoustic signal to the liquid to cause the interface to oscillate with a second mode of oscillation that is different from the first mode of oscillation, thereby creating a second streaming pattern having second streamlines within the liquid that is different than the first streaming pattern,
- wherein the second streamlines cross the first streamlines to produce chaotic mixing of the liquid.
2 more elements
A method of mixing, including:
- providing a fluid in a well so as to establish an acoustic field gradient;
- and
- applying a first acoustic signal to the fluid to cause the acoustic field gradient to oscillate with a first mode of oscillation, thereby creating a first streaming pattern having first streamlines within the fluid;
- and
- after applying the first acoustic signal, applying a second acoustic signal that is discretely separate from the first acoustic signal to the fluid to cause the acoustic field gradient to oscillate with a second mode of oscillation, thereby creating a second streaming pattern having second streamlines within the fluid that is different than the first streaming pattern, the second mode of oscillation being different than the first mode of oscillation;
- wherein the second streamlines cross the first streamlines to produce chaotic mixing of the fluid.
3 more elements
A method of mixing, the method comprising:
- forming a bubble within a fluid;
- and
- applying a first acoustic signal to the fluid to cause the bubble to oscillate with a first mode of oscillation, thereby creating a first streaming pattern having first streamlines within the fluid;
- and
- after applying the first acoustic signal, applying a second acoustic signal that is discretely separate from the first acoustic signal to the fluid to cause the bubble to oscillate with a second mode of oscillation that is different from the first mode of oscillation, thereby creating a second streaming pattern having second streamlines within the fluid that is different than the first streaming pattern;
- wherein the second streamlines cross the first streamlines to produce chaotic mixing of the fluid.
3 more elements
Dependencies are inferred from the claim text.