Amorphous metal foam as a property-matched bone scaffold substitute
AssigneeCalifornia Institute of Technology
InventorsMarios D. Demetriou, John S. Harmon, William L. Johnson, Chris Veazey
Life of this patent
Estimating the term…
Abstract
Amorphous metal foams and methods of making the same are provided. The amorphous metal foams have properties matching those of natural bone, enabling their use as bone replacement scaffolds. In one embodiment, for example, an amorphous metal foam has a density-dependent stiffness (or Young's modulus, denoted E) ranging from about 640ρ3.75 τo αβouτ 2900ρ0.78, and a density dependent strength (σy) greater than about 8.1ρ2.57, wherein ρ (the density) is less than about 1.7 g/cc.
Claims12
An amorphous metal foam formed from the expansion of bubbles entrained in the undercooled liquid of the amorphous metal at a temperature above the glass transition temperature, but below the melting temperature of the amorphous metal, wherein the amorphous metal foam having a cell volume fraction and size distribution substantially matching that of natural bone, and comprising a density-dependent stiffness in units of megapascal ranging from about 640ρ3.75 to about 2900ρ0.78, and a density dependent strength in units of megapascal greater than about 8.1ρ2.57, wherein ρ is the density in units of g/cc and is less than about 1.7 g/cc.
A method of making an amorphous metal foam, the method comprising:
- mixing a metal alloy liquid with a chemical non-reacting propellant gas to form bubbles;
- sealing the mixture in a container in an inert gas atmosphere at an initial pressure;
- holding the mixture at an initial temperature above a glass transition temperature of the metal alloy and above a melting point of the metal alloy;
- reducing the temperature of the mixture to an optimum temperature above the glass transition temperature of the metal alloy and below the melting point of the metal alloy;
- holding the mixture at the optimum temperature for a duration no longer than the time required to crystallize the alloy at that temperature while reducing the initial pressure to an optimum pressure below the initial pressure to effect expansion of the bubbles;
- and
- quenching the mixture to a final temperature below the glass transition temperature of the metal alloy to produce an amorphous metal foam.
Dependencies are inferred from the claim text.