Injectible cyanoacrylate-functionalized polyisobutylenes
AssigneeThe University of Akron
InventorsJoseph P. Kennedy, Yongmoon Kwon, Suresh Jewrajka
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Abstract
The present invention generally relates to injectible polyisobutylene polymer compounds. More specifically, the present invention relates to injectible polyisobutylene polymer compounds that are designed for various biological and medical applications. In one embodiment, the present invention relates to injectible functionalized polyisobutylene polymer compounds that are designed for various biological and medical applications. In another embodiment, the present invention relates to injectible cyanoacrylate-functionalized polyisobutylene polymer compounds.
Claims32
An injectible functionalized polyisobutylene compound comprising:
- a core structure having at least three polyisobutylene arms connected thereto,
- wherein each of the polyisobutylene arms contain a pendant group selected from a cyanoacrylate group, a —NH2 group, a -NEt2 group.
An injectible functionalized polyisobutylene compound comprising:
- a core structure having at least three polyisobutylene arms connected thereto,
- wherein each of the polyisobutylene arms contain a pendant cyanoacrylate group and wherein the Mn of the compound is in the range of about 1,500 g/mole to about 4,500 g/mole.
An injectible functionalized polyisobutylene compound comprising:
- a core structure having at least three polyisobutylene arms connected thereto,
- wherein each of the polyisobutylene arms contain a pendant —NH2 group and wherein the Mn of the compound is in the range of about 1,500 g/mole to about 4,500 g/mole.
An injectible functionalized polyisobutylene compound comprising:
- a core structure having at least three polyisobutylene arms connected thereto,
- wherein each of the polyisobutylene arms contain a pendant -NEt2 group and wherein the Mn of the compound is in the range of about 1,500 g/mole to about 4,500 g/mole.
A method for forming a network from an injectible functionalized polyisobutylene compound, the method comprising the steps of:
- (A) combining at least one injectible functionalized polyisobutylene compound and at least one initiator compound, wherein the at least one injectible functionalized polyisobutylene compound comprises a core structure having at least three polyisobutylene arms connected thereto and wherein each of the polyisobutylene arms contain a pendant group selected from a cyanoacrylate group, a —NH2 group, a -NEt2 group;
- (B) loading the combination of the at least one injectible functionalized polyisobutylene compound and at least one initiator compound into an injection device;
- and
- (C) injecting the combination of the at least one injectible functionalized polyisobutylene compound and at least one initiator compound into an environment suitable to cause the formation of a polymer network.
An injectible functionalized polyisobutylene blend comprising:
- a first functionalized polyisobutylene compound comprising a core structure having at least three polyisobutylene arms connected thereto,
- wherein each of the polyisobutylene arms contain a pendant cyanoacrylate group;
- and
- a second functionalized polyisobutylene compound comprising a core structure having at least three polyisobutylene arms connected thereto,
- wherein each of the polyisobutylene arms contain a pendant group selected from a —NH2 group and a -NEt2 group.
Dependencies are inferred from the claim text.