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US 8,431,400 B2Granted
Dermal sheath cup cell population
AssigneeTrichoscience Innovations Inc.
InventorsRolf Hoffmann, Kevin J. McElwee
Life of this patent
Estimating the term…
Abstract
The present invention relates to a method for isolating hair follicle mesenchymal stem cells and to the use thereof for therapy and prophylaxis as well as for cosmetic treatments.
Claims6
A method for obtaining a dermal sheath cup cell population, the method comprising the following steps:
- a) preparing adult vital hair,
- b) cleaving the hair prepared in step a),
- c) isolating the attached dermal sheath cup together with the dermal hair papilla,
- d) separating the dermal hair papilla from the dermal sheath cup,
- e) propagating isolated cells from the dermal sheath cup obtained in step d) in cell culture for more than one passage, and
- f) obtaining the dermal sheath cup cell population.
3 more elements
An isolated adult dermal sheath cup cell population having the characteristics of forming a completely new hair follicle, of migrating into a pre-existing hair papilla, of forming a part of the dermal connective tissue coating and of having a lower alkaline phosphatase activity than cells of the dermal papilla.
Dependencies are inferred from the claim text.