Binned micro-vessel density methods and apparatus

A method of automatically obtaining micro-vessel density (MVD) measurements from an image of biological vasculature containing a plurality of vessels, the method comprising acts of:

• automatically identifying a plurality of vessel regions in a region of interest of the image;
• automatically determining a vessel size associated with each of the plurality of vessel regions;
• automatically associating each of the plurality of vessel regions with one of a plurality of bins based on the vessel size associated with the respective vessel region;
• and
• automatically computing, for each of the plurality of bins, at least one measurement associated with the MVD of vessel regions associated with the respective bin.

A non-transitory computer readable medium encoding instructions capable of being executed on one or more processors, the instructions, when executed, performing a method of automatically obtaining micro-vessel density (MVD) measurements from an image of biological vasculature containing a plurality of vessels, the method comprising acts of:

• automatically identifying a plurality of vessel regions in a region of interest of the image;
• automatically determining a vessel size associated with each of the plurality of vessel regions;
• automatically associating each of the plurality of vessel regions with one of a plurality of bins based on the vessel size associated with the respective vessel region;
• and
• automatically computing, for each of the plurality of bins, at least one measurement associated with the MVD of vessel regions associated with the respective bin.