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US 8,425,926 B2Granted
Antimicrobial medical devices
OwnerYongxing Qiu, John Martin Lallyinventors
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Abstract
The present invention provides methods for making an antimicrobial medical device, preferably an antimicrobial ophthalmic device, more preferably an antimicrobial extended-wear contact lens, which contains silver nano-particles distributed uniformly therein. The antimicrobial medical device can exhibit antimicrobial activity over an extended period of time.
Claims17
A method for making an antimicrobial medical device, comprising the steps of:
- obtaining a polymerizable fluid composition comprising a siloxane-containing macromer and a vinylic monomer capable of reducing silver cations;
- adding a desired amount of a soluble silver salt into the fluid composition to form a polymerizable dispersion comprising silver nanoparticles and said silver nanoparticles having a stability of at least about 60 minutes, wherein the silver nanoparticles are formed by reducing the silver cations in the soluble silver salt with the vinylic monomer;
- introducing an amount of the polymerizable dispersion in a mold for making a medical device;
- and polymerizing the polymerizable dispersion in the mold to form the antimicrobial medical device containing silver nanoparticles.
1 more element
Dependencies are inferred from the claim text.