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US 8,425,898 B2Granted
Compositions, methods, and kits for eliciting an immune response
AssigneeDuke University
InventorsJohn H. Sampson, Duane A. Mitchell
Life of this patent
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Abstract
The present invention relates to compositions, methods, and kits for eliciting an immune response to at least one CMV antigen expressed by a cancer cell, in particular for treating and preventing cancer. CMV determination methods, compositions, and kits also are provided.
Claims8
A method for eliciting in a subject an immune response to a cancer cell that expresses a CMV antigen, the method comprising:
- selecting a subject in need of treatment related to the presence of the cancer cell;
- detecting the expression of the CMV antigen by the cancer cell in the subject, and
- administering to the subject a pharmaceutically acceptable composition comprising at least one CMV antigen, wherein the pharmaceutically acceptable composition, when administered to the subject, elicits an immune response to the cancer cell.
Dependencies are inferred from the claim text.