Aneurysm occlusion device containing bioactive and biocompatible copolymer shell and biocompatible metallic frame member
AssigneeWisconsin Alumni Research Foundation
InventorsRoham Moftakhar, Kristyn S. Masters, Wendy C. Crone, Fangmin Xu
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Abstract
An endovascular device for occluding a vascular aneurysm is disclosed. The device includes a polymeric shell member that, in one embodiment, may be constructed from a bioactive and biocompatible polyurethane-diol-glycosaminoglycan copolymer, and a biocompatible metallic frame member. The copolymer is sufficiently flexible and strong for endovascular delivery into a vascular aneurysm and for use as a polymeric shell for receiving the biocompatible metallic frame member. The biometallic frame member may include one or more components constructed from a NiTi alloy.
Claims25
An endovascular medical device comprising:
- a polymeric member defining an interior chamber, wherein the polymeric member is constructed from a copolymer comprising a biocompatible polyurethane and a bioactive polysaccharide, wherein the bioactive polysaccharide is incorporated into the biocompatible polyurethane backbone of the copolymer;
- and
- a biocompatible metallic frame member comprising one or more components constructed from a NiTi alloy having a transformation temperature below a patient's body temperature, disposed within the interior chamber, and adapted to structurally support the polymeric member.
An endovascular medical device comprising:
- a polymeric member defining an interior chamber and constructed from an elastic, hemocompatible polymer, wherein the elastic, hemocompatible polymer is modified with an anti-thrombotic agent and wherein the elastic, hemocompatible polymer is a member selected from the group consisting of poly(ethylene glycol), poly(vinyl alcohol), polytetrafluoroethylene, polyethylene terephthalate, poly(hydroxyethyl methacrylate), poly(hydroxyethyl acrylate), and a copolymer thereof, and,
- a biocompatible metallic frame member comprising one or more components constructed from a NiTi alloy having a transformation temperature below a patient's body temperature, disposed within the interior chamber, and adapted to structurally support the polymeric member.
Dependencies are inferred from the claim text.