Simulation system of cardiac function, simulation method of cardiac function, simulation program of cardiac function, and composite material sheet

A simulation method of cardiac function using at least one sufficiently programmed computer to simulate a change in ventricular geometry by computation wherein the simulation method utilizes a cardiac structure model to represent a heart made of the myocardial tissue comprising both myocyte and connective tissues as continuum data of a composite material containing matrix and reinforcement fiber, comprising:

• inputting connective tissue data representing mechanical property of the connective tissue within the myocardial tissue ad myocyte data representing mechanical property of the myocyte within the myocardial tissue and storing the connective tissue data and the myocite data into a memory;
• inputting geometry data of three-dimensional geometry of all or any part of the heart and storing the geometry data into the memory;
• generating the cardiac structure model that represents the three-dimensional geometry as assembly of finite elements, setting a mechanical property and a direction of the reinforcement fiber with respect to at least one of the finite elements and setting a mechanical property of the matrix with respect to at least one of the finite elements, wherein the mechanical property represented by the myocyte data is set as a mechanical property of the matrix and the mechanical property represented by the connective tissue data is set as a mechanical property of the reinforcement fiber;
• and
• determining a boundary condition and calculating a change in geometry of the heart represented by the cardiac structure model under a pressure load according to the boundary condition.

A non-transitory recording medium that stores a simulation program of cardiac function by directing a computer to execute a simulation of a change in ventricular geometry wherein the simulation program utilizes a cardiac structure model to represent a heart made of the myocardial tissue comprising both myocyte and connective tissue as continuum data of a composite material containing matrix and reinforcement fiber, the simulation program directs the computer to execute:

• a computation processing to input both connective tissue data representing mechanical property of the connective tissue within myocardial tissue and myocyte data representing mechanical property of the myocyte within the myocardial tissue;
• a computation processing to input geometry data of three-dimensional geometry of all or any part of the heart;
• a cardiac-structure-model construction processing to generate the cardiac structure model that represents the three-dimensional geometry as an assembly of finite elements, set a mechanical property and a direction of the reinforcement fiber with respect to at least one of the finite elements and set a mechanical property of the matrix with respect to at least of one of the finite elements, wherein the mechanical property represented by the myocyte data is set as a mechanical property of the matrix and the mechanical property represented by the connective tissue data is set as a mechanical property of the reinforcement fiber;
• and
• a computation processing to determine a boundary condition and calculate a change in geometry of the heart represented by the cardiac structure model under a pressure load according to the boundary condition.