Methods for detection and identification of cell type
AssigneeThe United States of America as represented by the Secretary of the Army
InventorsCharles H. Wick, Michael F. Stanford, Alan W. Zulich, Samir V. Deshpande, Rabih E. Jabbour, Jacek P. Dworzanski, Patrick E. McCubbin
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Abstract
A process is provided for identifying a cell type in a sample that includes identification of one or more peptide sequences in the sample. Each peptide sequence is assigned to a protein of known sequence. A matrix of assignments is generated for the presence or absence of each peptide in one or more cells. The matrix of assignments is rearranged according to cell classification. A cell type based on the most probable cell classification is identified.
Claims9
A process of identifying a cell type in a sample, comprising:
- identifying one or more peptide sequences in said sample on a mass spectrometer;
- assigning each peptide to a protein of known sequence;
- generating a matrix of assignments for a presence or absence of each peptide in one or more cells;
- rearranging said matrix of assignments according to cell classification;
- and
- identifying the cell type based on the most probable cell classification.
Dependencies are inferred from the claim text.