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US 8,412,333 B2Granted
Neurostimulator involving stimulation strategies and process for using it
AssigneeNeuroPace, Inc.
InventorBenjamin D Pless
Life of this patent
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Abstract
This is a neurostimulator that is configured to treat epilepsy and other neurological disorders using certain stimulation strategies, particularly changing various pulse parameters, during the imposition of a burst of those pulses. The invention includes the processes embodying those stimulation strategies.
Claims5
A method for treating an abnormal neurological condition comprising:
- detecting electrical activity of brain tissue wherein the detected electrical activity is characterized by at least one detected parameter;
- applying a plurality of bursts of electrical stimulation to the brain tissue, wherein each burst of the plurality of bursts comprises a determined number of electrical pulses being characterizable by a plurality of burst parameters;
- and
- varying at least one of the burst parameters during at least a portion of the time the plurality of bursts of electrical stimulation is applied to vary the bursts so that the burst parameters of at least one burst of the plurality of bursts are different from the burst parameters of at least one other burst of the plurality of bursts, wherein the varying is based on a timing of the at least one detected parameter.
1 more element
A method for treating an abnormal neurological condition comprising:
- detecting electrical activity of brain tissue wherein the detected electrical activity is characterized by at least one detected parameter;
- applying a plurality of bursts of electrical stimulation to the brain tissue, wherein each burst of the plurality of bursts comprises a determined number of electrical pulses being characterizable by a plurality of burst parameters and at least one burst of the plurality of bursts is applied at a time that is synchronized to a time at which the at least one detected parameter is detected;
- and
- varying at least one of the burst parameters during at least a portion of the time the plurality of burst parameters of electrical stimulation is applied to vary the bursts so that the burst parameters of at least one burst of the plurality of bursts are different from the burst parameters of at least one other burst of the plurality of bursts.
1 more element
A method for treating an abnormal neurological condition comprising:
- detecting a rate of electrical activity in signals sensed from brain tissue;
- identifying an interval corresponding to the detected rate;
- applying a plurality of bursts of electrical stimulation to the brain tissue, wherein each burst of the plurality of bursts comprises a determined number of electrical pulses being characterizable by a plurality of burst parameters and at least one burst of the plurality of bursts is applied based on detection of the interval;
- and
- varying at least one of the burst parameters during at least a portion of a time the plurality of bursts of electrical stimulation is applied to vary the bursts so that the burst parameters of at least one burst of the plurality of bursts are different from the burst parameters of at least one other burst of the plurality of bursts.
2 more elements
Dependencies are inferred from the claim text.