Hemostasis valve and guidewire pacing system

A vascular access system comprising:

• a guide catheter having a distal portion and a proximal end, an electrode disposed on the distal portion, a first electrical contact disposed on the proximal end, a first lumen extending between the distal portion and the proximal end, and a first conductor extending between the electrode and the first electrical contact;
• a hemostasis valve having a valve body including a distal end and a proximal end, a second lumen extending between the distal and proximal ends, a valve disposed in the lumen, a second electrical contact disposed on the distal end and a second conductor connecting the second electrical contact with a proximal portion of the valve body;
• wherein the guide catheter proximal end and the hemostasis valve distal end are removably connected to one another;
• wherein the first and second electrical contacts are electrically coupled to one another, forming an electrical pathway between the hemostasis valve and the electrode;
• wherein the first and second lumens are fluidly connected to one another, forming a fluid pathway;
• and
• wherein the fluid pathway is fluidly and electrically isolated from the first and second conductors, the first and second electrical contacts and the electrode.