Cardiac resynchronization therapy optimization using vector measurements obtained from realtime electrode position tracking

One or more non-transitory computer-readable storage media comprising processor-executable instructions to configure a computing device to:

• select a first pair of electrodes to define a first vector and selecting a second pair of electrodes to define a second vector;
• for each of the first and second pairs of electrodes, acquire coordinate position information at each of a plurality of fiducial points within a cardiac cycle, wherein the acquiring comprises establishing an electrical localization field in the patent and using each of the electrodes for measuring one or more electrical potentials in the electrical localization field;
• and
• determine a first vector metric based on the acquired coordinate position information for the first pair of electrodes, and determining a second vector metric based on the acquired coordinate position information for the second pair of electrodes.