Systems and methods for spatio-temporal analysis
AssigneesThe Charles Stark Draper Laboratory, Inc., Tufts Medical Center, Inc.
InventorsRami Mangoubi, Mukund Desai, Adel Malek, Andrew Copeland
Life of this patent
Estimating the term…
Abstract
High resolution time sequences of 3D images that show the dynamics of a time varying changes are provided. The 3D time series of images representing an object that include time varying changes may be produced from lower dimensional image time sequences, such as 2D images. The 2D images may be generated using angiography and may include fluid flow information (e.g., arrival times). The fluid flow information may be provided, for example, by injecting a chemical into the fluid and analyzing its position in the object or body over time. A varying contrast model may be applied to determine the location of the chemical at different points in time which may assist in detecting an ailment.
Claims25
A method for producing a three-dimensional time-series of images representing an object that include time varying changes comprising fluid flow or other movements using lower dimensional images comprising two-dimensional time sequences and a static constraints 3-D map, the method comprising:
- receiving, by a processor, a first plurality of two-dimensional time series images, wherein the first plurality of images correspond to a first axis of the three-dimensional object, and wherein the first plurality of images include an indicia of time varying changes;
- and
- reconstructing, by the processor, the three-dimensional time series of images by combining the first plurality of images with the static 3-D map, wherein the reconstructed three-dimensional images include the indicia of time varying changes of the first plurality of images, wherein the combining comprises iteratively processing a data fusion equation that includes a spatial parameter and temporal parameter to output either a spatial or temporal result at each iteration.
A system for producing a three-dimensional time-series of images representing an object that include time varying changes comprising fluid flow or other movements using lower dimensional images comprising two-dimensional time sequences and a static constraints 3-D map, the system comprising:
- a processor operable to:
- receive a first plurality of two-dimensional time series images, wherein the first plurality of images correspond to a first axis of the three-dimensional object, and wherein the first plurality of images include an indicia of time varying changes;
- and
- reconstruct the three-dimensional time series of images by combining the first plurality of images with the static 3-D map, wherein the reconstructed three-dimensional images include the indicia of time varying changes of the first plurality of images, wherein the combining comprises iteratively processing a data fusion equation that includes a spatial parameter and temporal parameter to output either a spatial or temporal result at each iteration.
A non-transitory computer readable medium having computer readable program codes embodied therein for producing a three-dimensional time-series of images representing an object that include time varying changes comprising fluid flow or other movements using lower dimensional images comprising two-dimensional time sequences and a static constraints 3-D map, the computer readable medium program codes performing functions comprising:
- receiving a first plurality of two-dimensional time series images, wherein the first plurality of images correspond to a first axis of the three-dimensional object, and wherein the first plurality of images include an indicia of time varying changes;
- and
- reconstructing the three-dimensional time series of images by combining the first plurality of images with the static 3-D map, wherein the reconstructed three-dimensional images include the indicia of time varying changes of the first plurality of images, wherein the combining comprises iteratively processing a data fusion equation that includes a spatial parameter and temporal parameter to output either a spatial or temporal result at each iteration.
Dependencies are inferred from the claim text.