Methods for the synthesis of organic sulfides by using sulfides and organic sulfur-indium complexes
AssigneeKnu-Industry Cooperation Foundation
InventorPhil-ho Lee
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Abstract
The present invention relates to a novel synthesis method for the formation of carbon-sulfur bonds by the reaction of an organic sulfur-indium complex with nucleophile in the presence of a palladium catalyst. The present invention provides a synthesis method to prepare several kinds of organic sulfides which are difficult to be prepared by the conventional synthesis methods. A short reaction time and quantitative yield are the advantages of this method. In addition, several kinds of organic sulfide can be prepared by the selection of nucleophile and organic sulfur-indium complex to be used.
Claims9
A method for the preparation of an organic sulfide compound of formula 1 comprising,
- reacting a nucleophile of formula 3 and an organic sulfur-indium complex of formula 2 to form the organic sulfide compound of formula 1, wherein in formula 1 R1 is derived from the nucleophile of formula 3 and R is derived from the organic sulfur-indium complex of formula 2,
- R1(SR)n formula 1
- In(SR)3 formula 2
- R1—Xm formula 3
- wherein
- m is 1 or 2;
- when m is 1, R1 is 1-naphthyl, 2-napthyhyl, 3-ethoxycargonylphenyl, 2-styryl, or ethoxycarbonyl-1-cyclohexane-2-yl, and n is 1;
- and when m is 2, R1 is
- and n is 2;
- R is a phenyl or a linear or branched alkyl group of 1 to 6 carbon atoms;
- and
- X is Cl, Br, I, —OSO2CF3, —OSO3CH3, —OC4H6CH3 iodonium of formula RI4PhBF4− or RI4Br−, wherein R is Ph, 2-thienyl, 4-methoxyphenyl, or trans-beta-styryl, or an azonium salt of formula —N2+X−, wherein X is Cl, Br, or I.
Dependencies are inferred from the claim text.