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US 8,410,181 B2Granted
Omega-3 diglyceride emulsions
AssigneeThe Trustees of Columbia University in the City of New York
InventorsRichard J. Deckelbaum, Yvon Carpentier
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Abstract
The present invention relates to omega-3 diglyceride emulsions characterized in that the lipid phase comprises at least about 40 wt.-% of diglycerides. Preferably about 70 wt. -% of the acyl-groups of said diglycerides, are eicosapentaenoic acid (EPA) groups and/or docosahexaenoic (DHA) groups. The invention further relates to methods of treatment using the omega-3 diglyceride emulsions.
Claims13
An omega-3 lipid-based oil-in-water emulsion suitable for administration to a patient, wherein
- (a) the emulsion comprises at least about 7% to about 35% omega-3 oil by weight in grams per 100 ml of emulsion,
- (b) the omega 3 oil comprises at least about 40% omega-3 diglyceride by weight per total weight of the omega-3 oil, and at least about 70 wt.-% of the acyl-groups of the omega-3 diglycerides comprise EPA, DHA or a mixture thereof,
- c) the omega-3 oil comprises less than about 10% omega 6 fatty acids, and
- d) the mean diameter of lipid droplets in the emulsion is less than about 5 microns.
1 more element
Dependencies are inferred from the claim text.