Composition and method for treating or preventing skeletal muscle fibrosis
OwnerMark Pines, Arnon Naglerinventors
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Abstract
A compound in combination with a pharmaceutically acceptable carrier, the compound having a formula: wherein: R1 is a member of the group consisting of hydrogen, halogen, nitro, benzo, lower alkyl, phenyl, and lower alkoxy; R2 is a member of the group consisting of hydroxy, acetoxy, and lower alkoxy; and R3 is a member of the group consisting of hydrogen and lower alkenoxy-carbonyl; and n is either 1 or 2; and pharmaceutically acceptable salts thereof; for use in treatment of or prevention of skeletal muscle fibrosis and/or for inducing skeletal muscle regeneration.
Claims5
A method for reducing the progression of skeletal muscle fibrosis in a subject having muscular dystrophy, the method comprising administering to the said subject a pharmaceutically effective amount of halofuginone or a pharmaceutically acceptable salts of halofuginone in combination with a pharmaceutically acceptable carrier.
A method for improving or inducing skeletal muscle regeneration in a subject having muscular dystrophy, the method comprising administering to the said subject a pharmaceutically effective amount of halofuginone or a pharmaceutically acceptable salts of halofuginone in combination with a pharmaceutically acceptable carrier.
Dependencies are inferred from the claim text.