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AssigneeApplied Pharmacy Services, Inc.
InventorsAlton Samuel Kelley, II, James Gregory Sullivan
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The present invention is directed to a pharmaceutical composition that includes a combination of about 2-5 milligrams of a non-steroidal anti-inflammatory drug and from about 2-30 milligrams of an opioid analgesic in a single pharmaceutical dosage unit that can provide effective chronic pain management with the added benefit of reduced side effects such as withdrawal and gastrointestinal disorders. The non-steroidal anti-inflammatory drug may be piroxicam and the opioid analgesic may be buprenorphine. The present invention also provides for a method of managing pain in a patient that includes administering the pharmaceutical composition previously described. The pharmaceutical composition previously described may be administered in a single or multiple dosage regimen.
A pharmaceutical formulation consisting essentially of piroxicam or meloxicam of 5 milligrams or less and buprenorphine of 2-30 milligrams, and a pharmaceutically acceptable excipient for reduction of chronic pain with reduced side effects.
A method of reducing chronic pain in a patient comprising administering to the patient, in one or more doses of a single pharmaceutical formulation consisting essentially of 2-5 milligrams of piroxicam or meloxicam and 2-30 milligrams of buprenorphine, and a pharmaceutically acceptable excipient.
Dependencies are inferred from the claim text.