Method for producing (1S,2R)-2-chloro-2-fluorocyclopropanecarboxylic acid
AssigneesSumitomo Chemical Company, Limited, Daiichi Sankyo Company, Limited
InventorsKeisuke Hatakeyama, Takashi Miki, Norihiko Hirata
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Abstract
The present invention provides a method for producing (1S,2R)-2-chloro-2-fluorocyclopropanecarboxylic acid with a high yield and high selectivity. Specifically, disclosed is a method for producing (1S,2R)-2-chloro-2-fluorocyclopropanecarboxylic acid, wherein (1S)-2-chloro-2-fluorocyclopropanecarboxylic acid ester is hydrolyzed using an esterase derived from Burkholderia cepacia.
Claims9
A method for producing (1S,2R)-2-chloro-2-fluorocyclopropanecarboxylic acid comprising hydrolyzing a (1S)-2-chloro-2-fluorocyclopropanecarboxylic acid ester using an esterase obtained from Burkholderia cepacia.
Dependencies are inferred from the claim text.