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US 8,409,800 B2Granted
Nucleic acid based fluorescent sensor for copper detection
AssigneeThe Board of Trustees of the University of Illinois
InventorsYi Lu, Juewen Liu
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Abstract
A nucleic acid enzyme responsive to copper, comprising an oligonucleotide comprising a nucleotide sequence of SEQ ID NO:1, wherein the nucleic acid enzyme is not self-cleaving.
Claims20
An isolated nucleic acid enzyme activated in the presence of copper, comprising an oligonucleotide comprising a nucleotide sequence shown in SEQ ID NO:
- 1, wherein the nucleic acid enzyme is not self-cleaving.
An isolated nucleic acid enzyme activated in the presence of copper, comprising:
- an oligonucleotide comprising a nucleotide sequence of SEQ ID NO:1, and
- a quencher, attached at a 3′ end of the nucleic acid enzyme.
Dependencies are inferred from the claim text.