Method for decreasing sebum production

A method for decreasing sebum secretion comprising administering to a patient in need thereof, an effective amount of a compound of the formula:

• in which R1 and R2 are each independently C1-6 alkyl;
• X is CH2;
• R3 is C1-6 aiki or pyridyl;
• p is 1;
• R4 is selected from the group consisting of C1-6 alkyl, C1-6 alkoxy, and SR7;
• R7 is C1-6 alkyl;
• or a pharmaceutically acceptable salt thereof.

A method for decreasing sebum secretion comprising administering to a patient in need thereof, an effective amount of a compound of the formula:

• in which R3 is C1-6 alkyl or pyridyl;
• R4 is selected from the group consisting of C1-6 alkyl, C1-6 alkoxy, and SR7;
• R7 is C1-6 alkyl;
• or a pharmaceutically acceptable salt thereof.

A method for treating acne comprising administering to a patient in need thereof, an effective amount of a compound of the formula:

• in which R1 and R2 are each independently C1-6 alkyl;
• X is CH2;
• R3 is C1-6 alkyl or pyridyl;
• p is 1;
• R4 is selected from the group consisting of C1-6 alkyl, C1-6 alkoxy, and SR7;
• R7 is C1-6 alkyl;
• or a pharmaceutically acceptable salt thereof.

An article of manufacture comprising a compound of the formula

• in which R1 and R2 are each independently C1-6 alkyl;
• X is CH2;
• R3 is C1-6 alkyl or pyridyl;
• p is 1;
• R4 is selected from the group consisting of C1-6 alkyl, C1-6 alkoxy, and SR7;
• R7 is C1-6 alkyl;
• or a pharmaceutically acceptable salt thereof, packaged for retail distribution, which advises a consumer how to utilize the compound to alleviate a condition selected from the group consisting of acne, oily skin, and seborrheic dermatitis.

A method for alleviating oily skin comprising administering to a patient in need thereof, an effective amount of a compound of the formula:

• in which R3 is C1-6 alkyl or pyridyl;
• R4 is selected from the group consisting of C1-6 alkyl, C1-6 alkoxy, and SR7;
• R7 is C1-6 alkyl;
• or a pharmaceutically acceptable salt thereof.

A method for treating acne comprising administering to a patient in need thereof an effective amount of a compound of the formula:

• in which R3 is C1-6 alkyl or pyridyi;
• R4 is selected from the group consisting of C1-6 alkyl, C1-6 alkoxy, and SR7;
• R7 is C1-6 alkyl;
• or a pharmaceutically acceptable salt thereof.

A method for treating seborrheic dermatitis comprising administering to a patient in need thereof an effective amount of a compound of the formula:

• in which R1 and R2 are each independently C1-6 alkyl;
• X is CH2;
• R3 is C1-6 alkyl or pyridyl;
• p is 1;
• R4 is selected from the group consisting of C1-6 alkyl, C1-6 alkoxy, and SR7;
• R7 is C1-6 alkyl;
• or a pharmaceutically acceptable salt thereof.

A method for treating seborrheic dermatitis comprising administering to a patient in need thereof, an effective amount of a compound of the formula:

• in which R3 is C1-6 alkyl or pyridyl;
• R4 is selected from the group consisting of C1-6 alkyl, C1-6 alkoxy, and SR7;
• R7 is C1-6 alkyl;
• or a pharmaceutically acceptable salt thereof.

An article of manufacture comprision a compound of the formula

• in which R3 is C1-6 alkyl or pyridyl;
• R4 is selected from the group consisting of C1-6 alkyl, C1-6 alkoxy, and SR7;
• R7 is C1-6 alkyl;
• or a pharmaceutically acceptable salt thereof, packaged for retail distribution, which advises a consumer how to utilize the compound to alleviate a condition selected from the group consistion of acne, oily skin, and seborrheic dermatits.