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US 8,409,594 B2Granted
Solid oil-in-water emulsion
AssigneeOtsuka Pharmaceutical Co., Ltd.
InventorsShigeo Shinohara, Fumiki Harano, Shinji Tsujimoto, Isamu Saeki
Life of this patent
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Abstract
The present invention aims to provide solid compositions comprising an oil-in-water emulsion that have sufficient hardness and good feel when used, and can sufficiently exhibit the physiological functions of an electrolyte. A solid composition is obtained by preparing an oil-in-water emulsion by combining a solid oil (A), a liquid oil (B), a surfactant (C), a polyhydric alcohol (D), an electrolyte (E), and water (F).
Claims18
A solid composition in the form of an oil-in-water emulsion comprising:
- at least one solid oil;
- at least one liquid oil;
- at least one non-ionic surfactant;
- at least one species of polyhydric alcohol selected from the group consisting of glycerol, diglycerol, ethylene glycol, diethylene glycol, polyethylene glycol, 1,3-butylene glycol, dipropylene glycol, and isoprene glycol;
- a plurality of electrolytes, wherein the plurality of electrolytes is a combination of (1) at least one first electrolyte selected from the group consisting of adenosine 3′,5′-cyclic phosphoric acid, adenosine monophosphate, adenosine diphosphate, adenosine triphosphate, and salts thereof, and (2) at least one second electrolyte selected from the group consisting of ascorbic acid, vitamin B1 (thiamin), ascorbic acid derivatives, vitamin B1 (thiamin) derivatives, and salts thereof;
- and
- water;
- wherein
- (i) the total concentration of solid oil in the solid composition is 15% to 30% by weight;
- (ii) the total concentration of liquid oil in the solid composition is 15% to 30% by weight;
- (iii) the concentration of water in the solid composition is 10% to 30% by weight;
- (iv) the plurality of electrolytes is present in the solid composition at a concentration of 1% to 15% by weight;
- (v) the water is present in a proportion of 20 to 60 parts by weight based on the total amount of 100 parts by weight of the solid oil and the liquid oil;
- (vi) the total concentration of nonionic surfactant in the solid composition is 3% to 10% by weight;
- and
- (vii) the total concentration of the at least one species of polyhydric alcohol in the solid composition is 15% to 25% by weight.
13 more elements
Dependencies are inferred from the claim text.