Biosensor coating composition and methods thereof
AssigneeAbbott Diabetes Care Inc.
InventorsNigel John Forrow, Shridhara Alva Karinka
Life of this patent
Estimating the term…
Abstract
The disclosure provides for reagent compositions for biosensors comprising release polymers, methods of making such biosensors and films of reagent compositions comprising release polymers. The reagent compositions comprise a release polymer and an effective analyte detecting amount of an enzyme an enzyme cofactor and a redox compound capable of acting in a biosensor as (i) a redox mediator associated with a working electrode (ii) a redox couple associated with a reference electrode or (iii) the redox mediator associated with the working electrode and the redox couple for the reference electrode.
Claims19
A method of coating a biosensor comprising:
- coating a reagent composition comprising:
- a polymer mixture comprising polyvinyl alcohol-polyethylene glycol graft copolymer and polyvinyl alcohol or a polymer mixture comprising polyvinyl acetate and polyvinylpyrrolidone and an effective analyte detecting amount of:
- an enzyme;
- an enzyme cofactor;
- and
- a redox compound capable of acting in a biosensor as
- (i) a redox mediator associated with a working electrode;
- (ii) a redox couple associated with a reference electrode;
- or
- (iii) the redox mediator associated with the working electrode and the redox couple for the reference electrode,
- on at least one electrode on the biosensor substrate providing a coated biosensor;
- and drying the coated biosensor to produce an analyte detecting composition film.
Dependencies are inferred from the claim text.