Confinement of kidney stone fragments during lithotripsy
AssigneeGenzyme Corporation
InventorsAlexander Schwarz, W. Scott McDougal
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Abstract
The present invention improves significantly the success rate of lithotripsy and reduces the risk of tissue damage, by injecting a temporary plug in front, and optionally behind a concretion (for extracorporeal lithotripsy) or behind a concretion (for intracorporeal lithotripsy). One aspect of the present invention relates to injecting an inverse thermosensitive polymer solution into a lumen, thereby preventing the migration of a concretion, or its fragments, upon extracorporeal or intracorporeal lithotripsy.
Claims19
A method of mitigating risk of damage to surrounding body tissue during lithotripsy on a concretion located in a lumen of the body, the method comprising:
- introducing a solution comprising an inverse thermosensitive polymer at a location distal to the concretion in the lumen;
- forming a temporary plug in the lumen distal to the concretion by gellation of the solution;
- deploying an energy source proximate to the concretion;
- and
- applying energy to the concretion with the energy source sufficient to fragment the concretion and propel one or more fragments of the concretion into the distal, temporary plug;
- wherein the temporary plug is configured such that it is capable of withstanding impact with fragments of the concretion and prevent further migration of the fragments down the lumen beyond the location of the temporary plug and the concretion is not contained, partially or completely, within the temporary plug prior to the application of energy thereto.
Dependencies are inferred from the claim text.