Peptides for development of diagnostic and therapeutic agents and methods of using same
AssigneePrince Henry's Institute of Medical Research
InventorsDavid Mark Milne-Robertson, Peter Gordon Stanton, Nicholas Francis Cahir
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Abstract
Novel immuno-interactive fragments of the αC portion of a mammalian inhibin α subunit, together with their variants and derivatives, produce antigen-binding molecules that are interactive with the αC portion, and which are chemically well defined and which can be produced in commercially significant quantities. The antigen-binding molecules of the invention can be used for the detection of a mammalian inhibin and for the treatment and/or prevention of conditions associated with aberrant levels of a mammalian inhibin.
Claims9
An antigen-binding molecule that is a monoclonal antibody and that binds specifically to an immuno-interactive fragment of an αC portion of a mammalian inhibin α-subunit, wherein the immuno-interactive fragment is a fragment consisting of or contained within residues 73-96 of SEQ ID NO:
- 2.
Dependencies are inferred from the claim text.