Polysaccharide gel formulation having multi-stage bioactive agent delivery
AssigneeAllergan, Inc.
InventorsDimitrios Stroumpoulis, Dustin Leslie, Christopher S. Mudd, Ahmet Tezel
Life of this patent
Estimating the term…
Abstract
Described herein are polysaccharide gel formulations including at least one inhibitor of polysaccharide degradation and methods of making the same. The methods described herein involve the steps of providing at least one polysaccharide and incorporating at least one inhibitor of degradation into the polysaccharide.
Claims10
A soft tissue augmentation system comprising a hyaluronic acid matrix having polysaccharide particles dispersed therein, the particles comprising chitosan cross-linked with tripolyphosphate (TPP) and coated with alginate, and said particles containing chondroitin sulfate A (CSA), wherein the matrix and/or the particles control the release of said CSA from the matrix and/or the particles and into the soft tissue.
Dependencies are inferred from the claim text.